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|Product Name:||Melanotan I||Specification:||10mg/vial|
Medical Polypeptide Hormones Melanotan I MT-1 10mg/vials Human Growth Hormone
Buy Peptide Melanotan I MT-1 from rina at pharmade dot com
MT 1 Model No.: Melanotan I 10mg/vial, 100vial/kit
Appearance: Sterile Filtered White lyophilized (freeze-dried) powder
Purity(by HPLC): >99.00%~99.90%
Total Impurities(by HPLC): 1.00%~0.05%
Single Impurity(by HPLC): <0.50%~0.08%
Origin: HK Shi jingu Technology Co.Ltd
Storage conditions: Aviod shunshine and keeping stoppered
Manufacuturers:Shenzhen Shi jingu Technology Co.Ltd
Shippping Express: HKEMS,EMS,UPS,TNT,HK-DHL,DHL,Fedex,TNT,etc
payment methods:Western Union,T/T,paypal,Bitcoins
Start with a dose of 1mg daily for the first two or three days and, if level of side effects permit, look to increase dosage by 0.25mg every day over the next several days until you reach a daily dosage of 2-3mg. This level should be adequate for most users, though some may wish to increase yet further, perhaps as high as 5mg daily in order to achieve a very deep tan. A maintenance phase as described above is then used.
Melanotan-1 Mechanism of Action - How it Works!
Melanotan produces its photoprotective effects by triggering a 'signaling cascade' via its activation of the MC1R on melanin-producing cells known as melanocytes. Upon Melanotan binding with the MC1R on the surface of melanocytes in the epidermal layer of the skin, it begins a series of actions and reactions that result in melanocytes favoring the production of eumelanin (photoprotective black/brown pigment). The initial binding activates the MC1R leading to the activation of adenylate cyclase (AC) and stimulation of the production of cyclic adenosine monophosphate (cAMP). cAMP in turn activates protein kinase A (PKA) resulting in the phosphorylation of the cAMP response element-binding (CREB). Phosphorylated CREB will bind to the cAMP response element (CRE) on the microphthalmia-associated transcription factor (MITF) gene leading to the synthesis of the MITF protein. MITF has the ability to activate several genes by binding to them, including the MC1R gene and the genes involved in melanogenesis. This results in increased concentrations of the melanogenic enzymes within the melanocyte.
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How to make an order :
1. Name what your need ( which product , quantity )
2. Full payment would be done once we come to an agreement on all details .
3. Parcel would be shipped out upon receipt of payment .
4. Info about parcel would be offered ( Photo , tracking number )
5. Finally you would get the parcel in 3 to 7 days .
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