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Procaine Hcl Pharmaceutical Raw Material Local Anesthetic Reduce Pain Procaine

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Procaine Hcl Pharmaceutical Raw Material Local Anesthetic Reduce Pain Procaine

China Procaine Hcl Pharmaceutical Raw Material Local Anesthetic Reduce Pain Procaine supplier
Procaine Hcl Pharmaceutical Raw Material Local Anesthetic Reduce Pain Procaine supplier Procaine Hcl Pharmaceutical Raw Material Local Anesthetic Reduce Pain Procaine supplier

Large Image :  Procaine Hcl Pharmaceutical Raw Material Local Anesthetic Reduce Pain Procaine

Product Details:

Place of Origin: China
Brand Name: email: lisa@pharmade.com
Certification: HPLC/SGS
Model Number: 51-05-8

Payment & Shipping Terms:

Minimum Order Quantity: 1kg
Price: Please contact
Packaging Details: 1kg/aluminium foil bag or as required
Delivery Time: Within 24 hours after receiving the payment
Payment Terms: T/T, Western Union, MoneyGram or Bitcoin
Supply Ability: Regular stock
Detailed Product Description
Product Name: Procaine Hcl Appearance: White Powder
Assay: 99% Standard: USP/BP
CAS Number: 51-05-8 Application: Local Anesthetic

 

 

Procaine Hcl Pharmaceutical Raw Material Local Anesthetic Reduce Pain Procaine

 

Description:

 

Procaine Hydrochloride

Atoxicaine

aminocaine

anadolor

anesthesol

anestil

atoxicocaine

bernocaine

 

potent local anesthetic

 

Procaine is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry.

 

Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically as novocaine. It acts mainly by being a sodium channel blocker. Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.

 

Pharmacology


The primary use for procaine is as a topical anaesthetic.

 

Procaine is the primary ingredient in the controversial preparation Gerovital H3 by Ana Aslan (Romania), which is claimed by its advocates to remedy many effects of aging. The mainstream medical view is that these claims were seriously studied and discredited in the 1960s.

 

A 1% procaine injection has been recommended for the treatment of extravasation complications associated with venipuncture (along with moist heat, ASA, steroids, antibiotics). It has likewise been recommended for treatment of inadvertent intra-arterial injections (10 ml of 1% procaine), as it helps 

relieve pain and vascular spasm.

 

Procaine is an occasional additive in illicit street drugs, such as cocaine. MDMA manufacturers also use procaine as an additive at ratios ranging from 1:1 up to 10% MDMA with 90% procaine, which can be life-threatening.

 

Adverse effects


Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine 

and serotonin levels in the brain. 

 

Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the 

myocardium leading to cardiac arrest.

 

Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA.

 

About one in 3000 white North Americans are homozygotic (i.e. they have two 

copies of the abnormal gene) for the commonest atypical form of the enzyme pseudocholinesterase,[10] which means that they do not hydrolyze ester anesthetics such as procaine.

 

The results in a prolonged period of high levels of the anesthetic in the blood and increased toxicity. However, there are populations in the world, such as the Vysya community in India, where deficiency of this enzyme is much more common.

 

 

 

 

Applications:

 

Procaine is used less frequently today since more effective (and hypoallergenic) alternatives such as lidocaine (Xylocaine) exist. Like other local anesthetics (such as mepivacaine, and prilocaine), procaine is a vasodilator, and is thus often coadministered with epinephrine for the purpose of vasoconstriction. 

 

Vasoconstriction helps to reduce bleeding, increases the duration and quality of anesthesia, prevents the drug from reaching systemic circulation in large amounts, and overall reduces the amount of anesthetic required.[6] Unlike cocaine, a vasoconstrictor, procaine does not have the euphoric and addictive qualities that put it at risk for abuse.

 

Procaine, an ester anesthetic, is metabolized in the plasma by the enzyme pseudocholinesterase through hydrolysis into para-amino benzoic acid (PABA), which is then excreted by the kidneys into the urine.

 

 

 

 

Specifications:

 

Product Name

Procaine Hcl

Molecular Formula

C13H21ClN2O2

Molecular Weight

272.77

Molecular Structure

Procaine Hcl Pharmaceutical Raw Material Local Anesthetic Reduce Pain Procaine

EINECS 200-077-2

Application

Tetracaine is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

 

 

 

 

Competitive Advantage:

 

· Professional packing: all of the products will be well packaged for safe shipping over the world.

· Efficient working: the order will be arranged for shipping within 24 hours after receiving the payment except on holidays.

· Fast delivery: the best shipping method will be chosen to guarantee the package delivered timely.

Contact Details
Shenzhen Shijingu Technology Co., Ltd.

Contact Person: Wendy

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